What us the therapeutic index (TI) of a drug?

The therapeutic index (TI) is indeed a quantitative measure of the relative safety of a drug. It is calculated by comparing the dose of the drug that produces a therapeutic effect to the dose that produces adverse effects. A higher therapeutic index indicates a greater margin of safety, meaning that the drug can be administered with a lower risk of producing harmful side effects relative to its therapeutic benefits.

This concept is essential in pharmacology as it helps healthcare professionals assess the safety profile of medications, guiding decisions on appropriate dosages and monitoring for adverse reactions. Understanding the therapeutic index allows practitioners to weigh the potential risks and benefits of a drug, ensuring that patients receive the most effective and safe treatment possible.