What is the primary use of cytocentrifugation in cytopreparation?

Cytocentrifugation is a technique mainly utilized for concentrating and preparing fluids that have low cellularity and low protein content. This process effectively separates cells from the surrounding fluid by spinning the sample at high speeds, resulting in cells being sedimented onto a slide in a monolayer, which is ideal for microscopy.

The ability to process fluids with low cellular content is particularly beneficial when the goal is to maximize the visibility and identification of cells with a reduced background of other components. By enhancing the concentration of cells, cytocentrifugation allows for better staining and analysis, which is vital in cytopathology and various diagnostic procedures.