What is the primary function of basophils in the immune response?

Basophils play a crucial role in the immune response, particularly in relation to allergic reactions and inflammation. They are a type of white blood cell that can release histamine and other chemicals that contribute to the inflammatory response during allergic reactions. Histamine is essential for the dilation of blood vessels and increased permeability, which allows other immune cells to reach sites of inflammation more effectively.

In allergic disorders, basophils can react to allergens by releasing these mediators, leading to symptoms commonly associated with allergies, such as itching, redness, and swelling. Their involvement is particularly evident in conditions like asthma, hay fever, and anaphylaxis. This function of assisting in the management of allergic reactions distinguishes basophils from other types of white blood cells that have different roles in the immune system, such as responding to viral or bacterial infections or producing antibodies.

Ultimately, the role of basophils in allergic disorders highlights their importance in the immune system's response mechanisms, particularly in hypersensitive reactions.