To ensure accuracy in staining in future QC and patient slides, what adjustment should be made to the SOP?

For ensuring accuracy in staining in future quality control (QC) and patient slides, it is essential to establish consistent and effective staining protocols. Dip the slide into hematoxylin more than twice enhances the staining intensity and ensures that tissue morphology is adequately defined. Hematoxylin is a vital stain, especially for highlighting cell nuclei; therefore, multiple dips can help achieve a more uniform and pronounced color, leading to more reliable histological assessments.

This adjustment can be particularly beneficial when dealing with slides that exhibit variable staining quality or for specific tissues that may require a deeper staining approach to visualize cellular details accurately. By fine-tuning the process in this manner, laboratory personnel can enhance the reproducibility of the results and support more accurate diagnoses from the stained slides.