A random urine specimen collected at 0730 at a PCC and not examined until 1100 hours should be:

In clinical laboratory practice, urine specimens are often analyzed to assess various health conditions, and the timing of the analysis is critical to preserving the integrity of the sample. When a random urine specimen is collected, it is ideal for it to be processed as soon as possible. However, if there is a delay—like in this scenario where the specimen is not examined for approximately 3.5 hours—it is essential to handle the specimen appropriately to minimize changes in its chemical composition and prevent bacterial growth.

Refrigerating the specimen at 4ºC is the recommended practice. Cooling the urine slows down enzymatic reactions and bacterial proliferation, helping to maintain its composition until it can be thoroughly analyzed. This temperature is optimal for preserving most analytes, such as glucose, proteins, and others, which could otherwise degrade or fluctuate if left at room temperature.

The other options pose risks to the sample's integrity. Keeping the urine at room temperature could lead to rapid bacterial growth and chemical changes. Freezing the sample is generally not advisable for routine analyses, as it can cause cellular lysis and alter the results of some tests. Sending the sample immediately would have been ideal, but since the question states it was not examined until later, refrigeration becomes the critical choice for managing